氯唑沙宗对脑血管疾病引发呃逆的疗效观察

目的 :观察氯唑沙宗对脑血管疾病引发呃逆症的治疗效果 ,探讨呃逆的发病机理及氯唑沙宗的药理作用。方法 :对 5 0例经颅脑CT证实为脑出血或脑梗死的患者 ,随机分为治疗组 :口服氯唑沙宗 0 .4g/次 ,3次 /d ;对照组 :口服胃复安 10mg/次 ,3次 /d ,并记录两组患者的治疗效果。结果 :两组的显效率分别为 80 %和 2 5 % (P <0 .0 1) ,总有效率分别为 93.3%和 4 5 % (P <0 .0 1)。两组比较差别有显著意义。结论 :本研究提示氯唑沙宗对脑血管疾病所引发的呃逆症有良好的治疗效果 ,且毒副作用少 ,值得推广。

The Observation on Chlorzoxazone's Curative Effect on Hiccup Caused by Cerebrovascular Disease

Objective:To observe the chlorzoxazone curative effect on hiccup caused by cerebrovascular disease, and to discuss the pathogenesis of hiccup and the pharmacology function of chlorzoxazone.Methods:50 cases of cerebral hemorrhage or cerebral infarction checked by CT were randomly divided into two groups: the treatment group (take chlorzoxazone orally 0.4g each time, three times a day)and the control group (take metoclopramide orally 10mg each time, three times a day). The treatment of results of two groups were recorded.Results: There was a remarkable meaning of comparing the difference of two groups. Conclusion: This research suggests that chlorzoxazone has a favorable treatment on hiccup caused by cerebrovascular disease and has little poisonous side effect .It is worth of popularization.