3-(Bromoacetyl)coumarins: unraveling their synthesis,chemistry, and applications |
| |
| Authors: | Moaz M. Abdou Ahmed Abu-Rayyan Ahmed G. Bedir S. Abdel-Fattah A. M. A. Omar Abdullah A. Ahmed El-Sayed I. El-Desoky Eslam A. Ghaith |
| |
| Affiliation: | Egyptian Petroleum Research Institute, Nasr City, Cairo 11727 Egypt.; Faculty of Science, Applied Science Private University, P. O. BOX 166, Amman 11931 Jordan ; Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo 11884 Egypt ; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516 Egypt |
| |
| Abstract: | This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)coumarin derivatives. Also, chemical reactions of 3-(bromoacetyl)coumarins as versatile building blocks in the preparation of critical polyfunctionalized heterocyclic systems and other industrially significant scaffolds are described. Recent advances of 3-(bromoacetyl)coumarins as attractive starting points towards a wide scale of five and six-membered heterocyclic systems such as thiophenes, imidazoles, pyrazoles, thiazoles, triazoles, pyrans, pyridines, thiadiazins as well as fused heterocyclic systems have been reported. Additionally, this review covers a wide range of analytical chemistry, fluorescent sensors, and biological applications of these moieties, covering the literature till May 2021.This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)coumarin derivatives. |
| |
| Keywords: | |
|
|
