| 麻黄对脂肪细胞脂质代谢影响的实验研究 |
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| 引用本文： | 蒋明,高久武司,奥田拓道. 麻黄对脂肪细胞脂质代谢影响的实验研究[J]. 中国中药杂志, 1999, 24(5): 302-304 |
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| 作者姓名： | 蒋明 高久武司 奥田拓道 |
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| 作者单位： | 南京中医药大学 南京 210029;日本爱媛大学医学部机器中心;日本爱媛夫大学医学部生化学第二 |
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| 摘 要： | 目的：研究麻黄对脂肪细胞脂质代谢的影响。方法：用正常大鼠附睾处脂肪细胞，分别观察麻黄对由１４Ｃ标记的葡萄糖转化的脂肪合成及由去甲肾上腺素（ＮＥ）促进的脂肪分解的作用。结果：麻黄可促进由葡萄糖转化的脂肪合成，并且这种作用与基质溶液的ｐＨ值有关；麻黄尚可抑制由ＮＥ促进的脂肪分解作用。结论：麻黄具有促进脂肪细胞脂肪合成的作用，该作用不是由麻黄碱所致，其作用机制与胰岛素有类同之处。
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| 关 键 词： | 麻黄 胰岛素 脂肪合成 脂肪分解 |
| 收稿时间： | 1997-07-30 |
Experimental Research of Ephedra sinica 's Influence on Lipid Metabolism of Lipocyte |
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| Jiang Ming;Takesi Takaku;Hiromichi Okuda. Experimental Research of Ephedra sinica 's Influence on Lipid Metabolism of Lipocyte[J]. China Journal of Chinese Materia Medica, 1999, 24(5): 302-304 |
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| Authors: | Jiang Ming Takesi Takaku Hiromichi Okuda |
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| Affiliation: | Nanjing University of Traditional Chinese Medicine, Nanjing 210029. |
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| Abstract: | Objective:To study the influence of Ephedra sinica on the lipid metabolism of lipocyte.Method:The rat's epididymal lipocytes were used to observe the effect of Ephedra sinica in lipogenesis from 14 C glucose and lipolysis promoted by norepinephrine (NE).Result:Ephedra sinica can promote lipogenesis from glucose, which is related with the pH value of matrix solution; and it also can inhibit the lipolysis promoted by NE.Conclusion:Ephedra sinica can promote the lipogenesis of lipocyte that is not induced by ephedrine, the mechanism being similar to that of insulin. |
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| Keywords: | Ephedra sinica insulin lipogenesis lipolysis |
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