Rosa机器人辅助立体定向颅内活检术的临床应用

目的 探讨Rosa机器人辅助下立体定向颅内活检术的临床应用效果.方法 回顾性分析2018年10月至2020年8月在Rosa机器人辅助下进行颅内占位立体定向活检术的33例病人的临床资料.结果 术中没有发生导航故障,所有程序都如期完成.33例进行76个靶点穿刺活检术,术后未发现颅内出血,术后无癫痫发作.33例活检阳性率为1...

Clinical application of Rosa robot-assisted stereotactic intracranial biopsy

Objective To explore the efficacy of Rosa robot-assisted stereotactic intracranial biopsy. Methods The clinical data of 33 patients with intracranial lesion who underwent Rosa robot-assisted stereotactic intracranial biopsy from October 2018 from August 2020. Results There was no navigation failure during the operation, and all procedures were completed successfully. Seven-six biopses were performed on these 33 patients, with no intracranial hemorrhage and epileptic seizures after the operation. The positive rate was 100%, including 21 patients with glioma, 5 with diffuse large B-cell lymphoma, 2 with vascular malformation, 1 with metastatic adenoma, 2 with germ cell tumor, 1 with anaplastic meningioma, and 1 with inflammatory demyelination. Of 21 patients with glioma, IDH-1 mutation was detected in 6 patients (28.6%), and MGMT promoter methylation was detected in 16 patients (76.2%). The loss of 1p/19q heterozygosity was found in 1 patient with anaplastic oligodendroglioma. Conclusions Rosa robot-assisted stereotactic frameless biopsy is a relatively safe and feasible operation, which can be used for histological and molecular diagnosis of intracranial lesions.