| 血清高尔基体蛋白73在慢性肝病患者中的临床应用 |
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| 引用本文： | 刘燕娜,姚明解,郑素军,陈香梅,刘向祎,胡鹏,欧启水,窦晓光,陈红松,段钟平,侯金林,南月敏,高志良,徐小元,庄辉,鲁凤民. 血清高尔基体蛋白73在慢性肝病患者中的临床应用[J]. 中华肝脏病杂志, 2022, 0(1): 4-8 |
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| 作者姓名： | 刘燕娜 姚明解 郑素军 陈香梅 刘向祎 胡鹏 欧启水 窦晓光 陈红松 段钟平 侯金林 南月敏 高志良 徐小元 庄辉 鲁凤民 |
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| 作者单位： | 北京大学基础医学院病原生物学系;北京大学基础医学院人体解剖学与组织胚胎学系;首都医科大学附属北京佑安医院肝病中心;首都医科大学附属北京同仁医院检验科;重庆医科大学附属第二医院感染病科;福建医科大学第一医院检验科;中国医科大学附属盛京医院感染科;北京大学人民医院肝病研究所;南方医科大学南方医院感染内科广东省肝脏疾病研究所;河北医科大学第三医院中西医结合肝病科;中山大学附属第三医院感染科;北京大学第一医院感染疾病科 |
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| 摘 要： | 高尔基体蛋白73（GP73）是细胞高尔基体上的一种跨膜蛋白，可被切割释放入血。近年来，越来越多的临床研究表明，血清GP73的升高与肝脏疾病密切相关，有望作为评估慢性肝脏疾病进展的新型血清学标志物。现围绕血清GP73对不同病因引起的慢性肝炎、肝纤维化、肝硬化和肝细胞癌中的临床应用进行综述，并对未来研究进行展望。
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| 关 键 词： | 高尔基体蛋白 肝脏疾病 肝脏炎症 肝纤维化 肝硬化 血清标志物 |
Clinical application of serum Golgi protein 73 in patients with chronic liver diseases |
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| Liu Yanna,Yao Mingjie,Zheng Sujun,Chen Xiangmei,Liu Xiangyi,Hu Peng,Ou Qishui,Don Xiaoguang,Chen Hongsong,Duan Zhongping,Hou Jinlin,Nan Yuemin,Gao Zhiliang,Xu Xiaoyuan,Zhuang Hui,Lu Fengmin. Clinical application of serum Golgi protein 73 in patients with chronic liver diseases[J]. Chinese journal of hepatology, 2022, 0(1): 4-8 |
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| Authors: | Liu Yanna Yao Mingjie Zheng Sujun Chen Xiangmei Liu Xiangyi Hu Peng Ou Qishui Don Xiaoguang Chen Hongsong Duan Zhongping Hou Jinlin Nan Yuemin Gao Zhiliang Xu Xiaoyuan Zhuang Hui Lu Fengmin |
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| Affiliation: | (Department of Microbiology and Center of Infectious Diseases,Peking University Health Science Center,Beijing 100191,China;Department oj Anatomy and Embtyology School of Basic Medical Sciences,Peking University Health Science Center,Beijing 100191,China;Liver Diseases Center,Beijing YouAn Hospital,Capital Medical University,Beijing 100069,China;Department of Clinical Laboratory,Beijing Tongren Hospital,Capital Medical University',Beijing 100730,China;Department of Infectious Diseases,The Second Affiliuted Hospital of Chongqing Medical University,Chongcjing 400010,China;Department of Laboratory Medicine,The First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,China;Department of Infectious Diseases,Shengjing Hospital,China Medical University,Shenyang 110022,China;Hepatology,Institute,Peking University People's Hospital,Beijing 100044,China;Guangdong Provincial Key Laboratory of Viral Hepatitis Research,Department of In fectious Diseases,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Department of Traditional and Western Medical Hepatology,Third Hospital of Hebei Medical University,Shijiazhuang 050051,China;Department of Infectious Diseases,The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Infectious Diseases,Peking University First Hospital,Beijing 100034,China) |
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| Abstract: | |
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| Keywords: | Golgi protein Liver cirrhosis Liver diseases Liver fibrosis Liver inflammation Serum biomarker |
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