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紫杉醇药物涂层球囊成形术治疗症状性椎动脉开口处狭窄的疗效
引用本文:刘佳明,潘鹏宇,陈立刚,赵玉龙,张海峰,董玉书,梁国标,高旭. 紫杉醇药物涂层球囊成形术治疗症状性椎动脉开口处狭窄的疗效[J]. 中国临床神经外科杂志, 2021, 26(2): 65-67. DOI: 10.13798/j.issn.1009-153X.2021.02.001
作者姓名:刘佳明  潘鹏宇  陈立刚  赵玉龙  张海峰  董玉书  梁国标  高旭
作者单位:110840 沈阳,中国人民解放军北部战区总医院神经外科(刘佳明、潘鹏宇、陈立刚、赵玉龙、张海峰、董玉书、梁国标、高 旭)
基金项目:国家重点研发计划项目(2016YFC1301703)。
摘    要:目的 探讨紫杉醇药物涂层球囊(P-DCB)成形术治疗症状性椎动脉开口狭窄的安全性和有效性.方法 回顾性分析2017年12月至2019年6月经P-DCB成形术治疗的43例症状性椎动脉开口处狭窄的临床资料.结果 所有病人均完成介入治疗,成功率为100%.术后即刻狭窄率[(12.03±2.15)%]较术前[(86.32±10...

关 键 词:椎动脉狭窄  药物涂层球囊  紫杉醇  椎动脉开口  球囊成形术

Paclitaxel drug-coated balloon angioplasty for patients with symptomatic vertebral artery origin stenosis
LIU Jia-ming,PAN Peng-yu,CHEN Li-gang,ZHAO Yu-long,ZHANG Hai-feng,DONG Yu-shu,LIANG Guo-biao,GAO Xu. Paclitaxel drug-coated balloon angioplasty for patients with symptomatic vertebral artery origin stenosis[J]. Chinese Journal of Clinical Neurosurgery, 2021, 26(2): 65-67. DOI: 10.13798/j.issn.1009-153X.2021.02.001
Authors:LIU Jia-ming  PAN Peng-yu  CHEN Li-gang  ZHAO Yu-long  ZHANG Hai-feng  DONG Yu-shu  LIANG Guo-biao  GAO Xu
Affiliation:Department of Neurosurgery, General Hospital of Northern Theater Command, PLA, Shenyang 110840, China
Abstract:Objective To evaluate the efficacy and safety of paclitacxel drug-coated balloon(P-DCB)angioplasty for the patients with symptomatic vertebral artery origin stenosis(VARS).Methods The clinical data of 43 consecutive patients with symptomatic VARS who underwent P-DCB angioplasty from December 2017 to June 2019 were analyzed retrospectively.Results All the procedures were completed successfully,and the success rate was 100%.The immediate postoperative stenosis rate[(12.03±2.15)%]was significantly lower than that[(86.32±10.26)%]before the operation(P<0.05).Arterial dissection occurred in 1 patient during the perioperative period.The follow-up ranged from 12 months to 16 months,with an average of 13.5 months.The symptomatic improvement rate was 95.3%(41/43).There was no statistical difference between the follow-up stenosis rate[(16.1±3.12)%]and the immediate postoperative stenosis rate(P>0.05).Restenosis occurred in 5 patients and the restenosis rate was 11.6%(5/43).Conclusion P-DCB angioplasty is a safe and good method for treatment of the patients with symptomatic VARS.
Keywords:Vertebral artery origin stenosis  Drug-coated balloon  Paclitacxel  Angioplasty
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