以肺血栓栓塞症为首发表现的再生障碍性贫血诊断及治疗策略一例报道

肺血栓栓塞症是临床常见的危重症之一,规范、足量的抗凝治疗是溶解肺动脉血栓、改善患者症状、降低死亡风险的重要手段。而对于同时合并血小板减少的肺血栓栓塞症患者,查找病因并明确诊断、预防出血与抗凝治疗仍是诊治难点。本文报道1例以肺血栓栓塞症为首发表现的再生障碍性贫血患者的临床诊治经过,以期提高临床工作者对该类疾病的认识。分析表明,再生障碍性贫血患者发生静脉血栓栓塞症风险较高,综合平衡抗凝获益及其出血风险、强化医患沟通是做出合理临床决策及治疗成功的关键。

Diagnosis and Treatment Strategy of Aplastic Anemia with Pulmonary Thromboembolism as the First Manifestation:a Case Report

Pulmonary thromboembolism is one of the common critical diseases in clinic.Standard and sufficient anticoagulant therapy is an important means to dissolve pulmonary artery thrombosis,improve patients'symptoms and reduce the risk of death.However,for patients with pulmonary thromboembolism complicated with thrombocytopenia at the same time,it is still difficult to find out the etiology and make clear diagnosis,prevent bleeding and anticoagulant therapy.This paper reports the clinical diagnosis and treatment of a aplastic anemia patient with pulmonary thromboembolism as the first manifestation,in order to improve the understanding of this kind of disease among clinical workers.The result shows that patients with aplastic anemia have a high risk of venous thromboembolism.Comprehensive balance of anticoagulant benefits and bleeding risk,and strengthening doctor-patient communication are the key to making reasonable clinical decisions and successful treatment.