| 酒炙大黄工业化生产工艺实验研究 |
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| 引用本文： | 刘峰,张伟,马存德,王月茹,何娟,王娟.酒炙大黄工业化生产工艺实验研究[J].中国药业,2011,20(14):44-46. |
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| 作者姓名： | 刘峰 张伟 马存德 王月茹 何娟 王娟 |
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| 作者单位： | 1. 陕西步长制药有限公司,陕西成阳,712000
2. 陕西中医学院,陕西成阳,712046 |
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| 基金项目： | "十一五"国家科技支撑计划项目;项目，陕西省重大科技创新专项项目;项目 |
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| 摘 要： | 目的优选符合工业化生产的酒炙大黄饮片生产工艺。方法采用L9(34)正交设计考察炒制温度、炒制时间、投料量,以饮片外观性状、总蒽醌含量为指标,选择高效液相色谱法进行含量测定,进行机械化炮制与传统手工炮制比对研究,确定最佳工艺技术参数。结果最佳炮制工艺技术参数为,加入10%黄酒拌匀,焖透,置XCYD-750型自控温旋盖电热炒药机内,炒炙温度设定140℃,炒炙时间设定15 min。结论优选工艺稳定可行,适合工业化生产。
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| 关 键 词： | 大黄 酒炙 工业化 工艺 |
Study on Industrialization Process of Rhubarb Decoction Pieces by Stir-frying with Wine |
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| Liu Feng,Zhang Wei,Ma Cunde,Wang Yueru,He Juan,Wang Juan.Study on Industrialization Process of Rhubarb Decoction Pieces by Stir-frying with Wine[J].China Pharmaceuticals,2011,20(14):44-46. |
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| Authors: | Liu Feng Zhang Wei Ma Cunde Wang Yueru He Juan Wang Juan |
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| Institution: | Liu Feng1,Zhang Wei1,Ma Cunde1,Wang Yueru2,He Juan1,Wang Juan1(1.Xianyang Buchang Pharmaceutical Co.,Ltd.,Xianyang,Shanxi,China 712000,2.Shannxi university of Traditional Chinese Medicine,China 712046) |
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| Abstract: | Objective To optimize industrialization process of Rhubarb decoction pieces by stir-frying with wine.Methods To determine the content of laetrile by orthogonal design,Factors of processing temperature,processing time,weight of Rhubarb decoction pieces were evaluated for their effects on extraction process.While the contents of nomadic and merchandise investigation of their crude drug were adopted as indexes.Determination of nomadic by High Performance Liquid Chromatography.Results Optimization precession wa... |
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| Keywords: | rhubarb decoction pieces stir-frying with wine industrialization processation |
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