HLA-A, B, C and DR antigens in immunoglobulin A deficiency |
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| Authors: | L Hammarström C I E Smith |
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| Institution: | Department of Clinical Immunology, Huddinge Hospital, Huddinge, Sweden and Department of Immunobiology, Wallenberg Laboratory, Lilla Frescati, Stockholm, Sweden |
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| Abstract: | HLA-A, B, C and DR typing was performed in 21 unrelated healthy blood donors with selective IgA deficiency (< 0.02 G/l of IgA). A significant increase in HLA A1 ( P < 0.05), HLA B8 ( P < 0.01) and HLA DR3 ( P < 0.001) was found. The frequency of HLA A28 was also increased ( P < 0.05). Furthermore, HLA A28 was present in all four donors lacking DR3. |
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