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中医药抗艾滋病优势的科学分析与前景展望
引用本文:刘延泽,许利嘉,肖 伟,彭 勇,王 健,肖培根.中医药抗艾滋病优势的科学分析与前景展望[J].医学教育探索,2012,43(9):1672-1684.
作者姓名:刘延泽  许利嘉  肖 伟  彭 勇  王 健  肖培根
作者单位:1.中国医学科学院 药用植物研究所,北京 100193 2.中国中医科学院 中医药防治艾滋病研究中心,北京 100700
基金项目:国家科技重大专项资助(2008ZX10005-004);科技部国际科技合作项目资助(2007DFB31610)
摘    要:在对艾滋病(AIDS)的发展过程、发病机制及防治对策进行概括性回顾的基础上,对近年通过各种筛选途径发现的抗艾滋病中药及其有效成分进行了总结,尤其对研究相对薄弱、难度大、前景看好的领域:蛋白质、多糖及鞣质的结构特性及可能的作用机制进行了较深入的剖析。科学地分析了中医药对AIDS的认识及治疗原理,详细论述了多靶点理论与新鸡尾酒疗法用于治疗AIDS的原理及策略,最后对人类战胜AIDS的途径进行了展望。

关 键 词:中医药  艾滋病  多靶点原理  新鸡尾酒疗法  鞣质

Scientific analysis and prospect outlook on advantages of traditional Chinese medicines against AIDS
LIU Yan-ze,XU Li-ji,XIAO Wei,PENG Yong,WANG Jian,XIAO Pei-gen.Scientific analysis and prospect outlook on advantages of traditional Chinese medicines against AIDS[J].Researches in Medical Education,2012,43(9):1672-1684.
Authors:LIU Yan-ze  XU Li-ji  XIAO Wei  PENG Yong  WANG Jian  XIAO Pei-gen
Institution:1.Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100193, China 2.Traditional Chinese Medicine to Fight AIDS Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China
Abstract:In this paper, based on the general overview in the development of AIDS, the pathogenesis, and prevention countermeasures, the anti-AIDS herbs and their active ingredients found in recent years through a variety of screening means are briefly summarized. Particularly, for the relative weak, difficult, but promising research fields, such as tannins, polysaccharides, and protein, their structural characteristics and possible mechanism of the action are more in-depth analyzed. Scientific analysis of awareness for AIDS and treatment principles by traditional Chinese medicines have been carried out. The theory of multi-target and the new cocktail principles and strategies for the treatment of AIDS are discussed in detail. Finally, the ways of defeating AIDS are prospectively proposed.
Keywords:traditional Chinese medicines (TCM)  AIDS  multi-target principle  new cocktail therapy  tannins
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