炼化企业作业职工恶性肿瘤流行病学调查研究

对锦州、抚顺、兰州、大连、锦西、南京、上海、大庆、独山子和茂名等十三个炼油厂做了癌症死亡率回顾性队列研究。队列成员５１８８９人，失访１７１７人（３．３１％）。结果表明：页岩型炼油厂队列成员肺癌的ＳＭＲ显著增高，肺癌与暴露程度间存在着剂量－反应关系。对于煤合成油厂的高暴露区（１９７１～１９８８年）的肺癌，通过Ｌｏｇｉｓｔｉｃ回归分析，调整其他环境混淆效应后，其ＯＲ值为９．２５。石油型炼厂队列成员全癌死亡率增高，在观察期内表现出上升趋势，胃癌、肝癌的ＳＭＲ分别为１．４３和１．５１，存在着明显的统计学意义。

Epidemiological Survey of Malignant Tumor Among Workers in petro-chemical Plant

A retrospective cohort study of cancer mortality at thirteen oil refineries in Jinzhou,Fushun,Lanzhou,Beijing,Dalian,Jinxi,Nianjing,Shanghai,Daqing and Maoming was conducted.51 889 employees were studied,with 1717 failed to follw-up(3. 31%)in the survey,The results showed that the SMR of lung cancer in employees of shale oil refineres was remarkably high,with a dose-response relationship between SMR of lung cancer and exposure level.The OR value of lung cancer from 1977 to 1988 in heavily exposed employees of the coal-synthetic oil refineries was 9.25 by adjusting other environmental confusion effects with logistic regression analysis.OR for all-cancer mortality was high in employees of natural oil refineries,which showed annual increasing trend with the period of observation. SMR of stomach and liver cancer were 1.43 and 1.51 respectively with statistical signifi