| 二硫化碳作业工人血清铜锌超氧化物歧化酶水平初探 |
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| 引用本文： | 简乐,胡迪生,谢晓敏. 二硫化碳作业工人血清铜锌超氧化物歧化酶水平初探[J]. 中国工业医学杂志, 1996, 9(4): 196-198 |
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| 作者姓名： | 简乐 胡迪生 谢晓敏 |
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| 作者单位： | 浙江医科大学预防医学系，杭州市职业病防治院 |
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| 摘 要： | 应用酶联免疫吸附试验（ＥＬＩＳＡ）对某化纤厂６４名二硫化碳（ＣＳ２）作业工人血清铜锌超氧化物歧化酶（ＣｕＺｎＳＯＤ）水平进行测定，结果显示接触ＣＳ２浓度高于１０ｍｇ／ｍ３及≤１０ｍｇ／ｍ３的工人血清ＣｕＺｎＳＯＤ水平均显著高于对照组（３８１．１８，３１２．５０和２３９．１０ｎｇ／ｍｌ，Ｐ＜０．０００１），呈一定剂量－效应关系。以装拆、纺丝等工段工人的血清ＳＯＤ水平增高为著。此外，应注意甄别年龄混杂因素对测定结果的影响。
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| 关 键 词： | 二硫化碳（CS2），酶联免疫吸附试验（ELISA），超氧化物歧化酶（SOD） |
The preliminary study on serum cuprozinc-superoxide dismutase levels in workers exposed to carbon disulfide |
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| Jian Le,et al.. The preliminary study on serum cuprozinc-superoxide dismutase levels in workers exposed to carbon disulfide[J]. Chinese Journal of Industrial Medicine, 1996, 9(4): 196-198 |
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| Authors: | Jian Le et al. |
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| Abstract: | An enzyme-linked immunosorbent assay(ELISA)was performed in 64 workers at a viscose rayon factory to detect their serum cuprozinc-superoxide dismutase(CuZnSOD)levels.The results showed that the average levels of CuZnSOD in workers exposed to carbon disulfide(CS2)both above and below 10 mg/m3 were higher than those of the control group(P<0.0001)and showed some dose-effect relationship.The contents of SOD in the filtering apparatus cleaners and spinners were distinctly high.Influence of aging and length of sevice was also discussed.It is suggested that serum SOD might be an objective indicator for monitoring the workers, health. |
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| Keywords: | carbon disulfide(CS2) enzyme-linked immunosorbent assay(ELISA) superoxide dismutase(SOD) |
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