| 磷霉素钠与加替沙星注射液配伍的稳定性考察 |
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| 引用本文： | 惠春,林大专,张凌赢,曾宪东,孙莹. 磷霉素钠与加替沙星注射液配伍的稳定性考察[J]. 中国药师, 2008, 11(12) |
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| 作者姓名： | 惠春 林大专 张凌赢 曾宪东 孙莹 |
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| 作者单位： | 长春医学高等专科学校,长春,130031 |
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| 摘 要： | 目的：考察磷霉素钠与加替沙星氯化钠注射液配伍变化，为临床合理用药提供参考依据。方法：在室温条件下观察及测定配伍液8h内的pH及外观变化，并检测配伍液中加替沙星的紫外光谱图和含量变化。结果：两药配伍后8h内配伍液的pH及外观无明显变化，而配伍液中加替沙星的紫外图谱和含量均有明显变化。结论：磷霉素钠不宜和加替沙星氯化钠注射液配伍使用。
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| 关 键 词： | 磷霉素钠 加替沙星 配伍 稳定性 |
Study the Stability on Compatibility of Fosfomycin Sodium with Gatifloxacin for Injection |
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| Hui Chun,Lin Dazhuan,Zhang Linying,Zeng Xiandong,Sun Ying. Study the Stability on Compatibility of Fosfomycin Sodium with Gatifloxacin for Injection[J]. China Pharmacist, 2008, 11(12) |
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| Authors: | Hui Chun Lin Dazhuan Zhang Linying Zeng Xiandong Sun Ying |
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| Affiliation: | Hui Chun Lin Dazhuan Zhang Linying Zeng Xi,ong Sun Ying (Changchun Medical College,Changchun,130031,China) |
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| Abstract: | Objective:To observe the compatibility of fosfomycin sodium with gatifloxacin for injection in 0.9% sodium chloride injection,provide reference for clinical rational drug use.Method:At room temperature for 8 hours,the content and UV spectra of fos- fomycin sodium with gatifloxacin for injection were determined by UV spectrophotometry and the change in appearance,pH value were observed.Result:There were no evident change in pH value and appearance after the mixture,but the content and UV spectra of the gatif... |
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| Keywords: | Fosfomycin sodium Gatifloxacin Compatibility Stability |
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