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Childhood‐onset schizophrenia case with 2.2 Mb deletion at chromosome 3p12.2–p12.1 and two large chromosomal abnormalities at 16q22.3–q24.3 and Xq23–q28
Authors:Danielle Rudd  Michael Axelsen  Eric A Epping  Nancy Andreasen  Thomas Wassink
Abstract:Childhood‐onset schizophrenia is rare, comprising 1% of known schizophrenia cases. Here, we report a patient with childhood‐onset schizophrenia who has three large chromosomal abnormalities: an inherited 2.2 Mb deletion of chromosome 3p12.2–p12.1, a de novo 16.7 Mb duplication of 16q22.3–24.3, and a de novo 43 Mb deletion of Xq23–q28.
Keywords:Childhood‐onset schizophrenia  copy number variant  cytogenetic  partial monsomy X  partial trisomy 16
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