| CD4+T细胞在肝细胞癌中的作用 |
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| 引用本文： | 许秀华,向晓星.CD4+T细胞在肝细胞癌中的作用[J].国际肿瘤学杂志,2013,40(10):785-788. |
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| 作者姓名： | 许秀华 向晓星 |
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| 作者单位： | 225501,苏北人民医院消化内科扬州大学临床医学院 |
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| 摘 要： | CD4+T细胞为一系列多功能细胞,研究发现肝细胞癌(HCC)中大部分CD4+T细胞亚群可通过活化或抑制机体固有免疫细胞、适应性免疫细胞及非免疫细胞等,参与肿瘤血管生成及浸润、肿瘤细胞凋亡、急性期蛋白及促癌基因的表达,进而发挥肿瘤促进或抑制作用.
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| 关 键 词： | 癌 肝细胞 免疫 CD4+T细胞 |
Roles of CD4+ T lymphocytes in hepatocellular carcinoma |
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| XU Xiu-hua
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XIANG Xiao-xing.Roles of CD4+ T lymphocytes in hepatocellular carcinoma[J].Journal of International Oncology,2013,40(10):785-788. |
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| Authors: | XU Xiu-hua XIANG Xiao-xing |
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| Institution: | Department of Gastroenterology, Northern Jiangsu People's Hospital; Clinical Medical College of Yangzhou University, Yangzhou 225501, China |
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| Abstract: | As a series of multifunctional cells, recent studies indicate that most of the CD4+ T lymphocyte subsets involve in the tumor angiogenesis and invasion, the apoptosis of tumor cells, and the expression of acute phase proteins and cancer-promoting genes by activating or inhibiting the innate immune cells, the adaptive immune cells and non-immune cells, thus function as tumor promoters or inhibitors in hepatocellular carcinoma. |
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| Keywords: | Carcinoma hepatocellular Immunity CD4 + T lymphocytes |
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