| B-慢性淋巴细胞白血病细胞的异质性——咐醇酯诱导后超微结构研究 |
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| 引用本文： | 齐淑玲,李卫萍,严文伟,刘津华,付津,王文杰. B-慢性淋巴细胞白血病细胞的异质性——咐醇酯诱导后超微结构研究[J]. 天津医药, 1991, 0(8) |
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| 作者姓名： | 齐淑玲 李卫萍 严文伟 刘津华 付津 王文杰 |
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| 作者单位： | 中国医学科学院血液学研究所，中国医学科学院血液学研究所，中国医学科学院血液学研究所，中国医学科学院血液学研究所，中国医学科学院血液学研究所，中国医学科学院血液学研究所 |
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| 摘 要： | 为研究B-CLL白血病细胞的发育,对9例B-CLL白血病细胞用咐醇酯(TPA)进行诱导试验,并对其诱导前后进行透射及扫描电镜观察,发现 B-CLL 细胞对 TPA 反应不同,其诱导后的形态也不同,表现明显的异质性,并发现部份病例经 TDA 诱导后呈现 HCL (毛白)诱导后的形态,为毛白亚型。
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| 关 键 词： | B-慢淋细胞白血病 TPA诱导 扫描电镜 透射电镜 异质性 |
Heterogeneity of Cells in B-Chronic Lymphocytic Leukemia,Ultrastructural Study after Exposure to TPA |
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| Qi Shuling,et al Institute of Hematology,Chinese Academy of Medical Sciences,Tianjin,China. Heterogeneity of Cells in B-Chronic Lymphocytic Leukemia,Ultrastructural Study after Exposure to TPA[J]. Tianjin Medical Journal, 1991, 0(8) |
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| Authors: | Qi Shuling et al Institute of Hematology Chinese Academy of Medical Sciences Tianjin China |
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| Abstract: | In order to study the development of leukemic cells in B-chronic lymphoid leuk-emia(B-CLL),TEM and SEM studies were performed in 9 cases before and after ex-posed to TPA.The results showed: lymphocytic cells in B-CLL responded differentlyto exposure to TPA in vitro in all cases examined in this study,and great heterogen-eity in morphology of B-CLL cells after TPA was found.Twocases of hairy cellleukemlavariant were examined after exposure to TPA. |
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| Keywords: | B-Chronic lymphocytic leukemia exposure to TPA scanning electron microscope transmission electron microscope heterogeneity |
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