纵隔巨大淋巴结增生症的诊断及外科治疗

目的：总结纵巨大淋巴增生症（giant lymph node hyperplasia）诊断和外科治疗的经验。方法：６例纵隔巨大淋巴结增生症病人，男女各３例，按Frizzera分类标准分为局灶性，多中心性ＨＶ型各１例、多中心性Ｍix型３例，ＰＣ型１例，均行手术治疗.结果：除１例多中心性Ｍix型病人术后４年复发，再接受第２次后术治疗，余５例病人均长期生存。结论：该症只要无系统功能严重受累，应积极考虑手术治疗，放射治疗效果不明显，但对多中心性或术中无法完全切除者，术后可考虎辅助放射治疗。

Diagnosis and surgical treatment of mediastinal giant lymph node hyperplasia

Objective: To review the experience of diagnosis and surgical treatment of giant lymph node hyperplasia (Castleman's disease). Methods: From June 1982 to June 1999, 6 patients with mediastinal giant lymph node hyperplasia underwent surgical treatment. There were 3 male and 3 female. One case with localized type and 5 with multicentric type were classified according to the criteria described by Frizzera. The diagnosis, treatment and prognosis were analyzed retrospectively. Results: Long term survival was achieved in 1 case with localized type and 4 with multicentric type, without recurrence. 1 case with multicentric type had recurrence 4 years later and underwent second operation. Conclusions: Operation is the first choice for patient with localized type or multicentric type without serious involvement of multiple system functions. Radiotherapy has no remarkable effect, but it should be taken into consideration postoperatively according to patient's condition, especially for patient with multicentric type disease.