介入疗法配合消癥扶正汤治疗肝癌24例疗效观察

目的:观察介入疗法配合消癥扶正汤治疗肝癌的临床疗效。方法:将45例肝癌患者随机分为2组。治疗组24例,采用介入疗法(经肝动脉插管灌注化疗药物及栓塞剂)并联合应用消癥扶正汤(药用黄芪、白术、茯苓、龙葵、当归、生地黄、五灵脂、枸杞子、白芍、川芎、香附、牡丹皮等)口服治疗;对照组21例,单纯应用介入疗法治疗。结果:近期有效率治疗组为79.2％,对照组为47.6％,2组比较,差异有显著性意义(P<0.05)。治疗后血白细胞(WBC)治疗组与治疗前比较,差异无显著性意义(P>0.05);但对照组下降明显,与治疗前比较,差异有显著性意义(P<0.05);2组治疗后比较,差异有显著性意义(P<0.05)。治疗后2组血清AFP均明显下降,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01);2组治疗后比较,差异有显著性意义(P<0.05)。2组治疗后卡氏评分比较,差异有显著性意义(P<0.05),治疗组优于对照组。结论:介入疗法配合消癥扶正汤治疗肝癌可提高疗效,并明显改善患者生活质量。

Treatment of Liver Cancer by Interventional Therapy Combined with Xiaozheng Fuzheng Tang: A Clinical Observation of 24 Cases

Objective: To observe the curative effect of in-terventional therapy (IT) combined with Xiaozheng Fuzheng Tang (XFT) for liver cancer (LC). Methods: 45 cases of LC were allocated to 2 groups randomly. The treatment group (24 cases) was treated by IT combined with XFT (composed of Radix Astragali,Rhizoma Atractylodis Macrocephalae, Poria, Herba Solani Nigri, Radix Angelicae Sinensis , Radix Rehmanniae, Faeces Trogopterori, Fructus Lycii, Radix Paeoniae Alba, Rhizoma Chuanxiong, Rhizoma Cyperi and Cortex Moutan, etc. )for oral use; the control group (21 cases) by IT alone. Results: In treatment group, the total effective rate was 79. 2% , and 47. 6% in control group ( P < 0. 05), after treatment, the WBC count showed no significant difference in compared with before treatment( P > 0. 05), but markedly decreased in control group compared with before treatment (P< 0.05). After treatment, the comparison between treatment group and control group, the decrease of WBC showed markedly significant difference ( P < 0. 05). The comparison between before and after treatment, the serum AFP of both groups were markedly decreased (P < 0. 05, P < 0. 01); the comparison between before and after treatment of both groups showed markedly significant difference ( P < 0. 05). The comparison of Car' s soring between both groups showed marked significant difference (P < 0. 05), and the treatment group is superior than that of control group. Conclusion: combined with XHF can increase the curative effect of LC and markedly improve the life quality.