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Ph chromosome in a patient with non-leukemic non-Hodgkin B-cell lymphoma |
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| Authors: | H Fujii H Yashige S Misawa S Tanaka Y Urata F Matuyama |
| Affiliation: | Third Department of Internal Medicine, Kyoto First Red Cross Hospital, Japan. |
| Abstract: | A standard Philadelphia translocation, t(9;22) (q34;q11), was found in lymph node cells from a patient with non-leukemic non-Hodgkin lymphoma at the time of diagnosis. The rearrangement of the breakpoint cluster region (bcr) was not detected with a bcr-3' probe. The neoplastic clone was of monoclonal B-cell character with E-, CD5-, CD10-, CD13-, CD19+, CD20+, CD21+, CD25-, HLA DR+, and positive surface Ig(kappa). The patient showed no evidence of chronic myelogenous leukemia. |
| Keywords: | Philadelphia chromosome bcr lymph node cells |