Infecciones de piel y partes blandas en pacientes hospitalizados: factores epidemiológicos,microbiológicos,clínicos y pronósticos |
| |
Authors: | Manuel Raya-Cruz Ignacio Ferullo María Arrizabalaga-Asenjo Antonio Nadal-Nadal María Paz Díaz-Antolín Margarita Garau-Colom Antonio Payeras-Cifre |
| |
Institution: | 1. Servicio de Medicina Interna y Enfermedades Infecciosas, Hospital Son Llàtzer, Palma de Mallorca, España;2. Servicio de Dermatología, Hospital Son Llàtzer, Palma de Mallorca, España;3. Servicio de Microbiología Clínica, Hospital Son Llàtzer, Palma de Mallorca, España |
| |
Abstract: | IntroductionSkin and soft-tissue infections (SSTIs) are a frequent cause of consultation in emergence services, and complicated cases require hospitalization. However there are few data in our setting about the clinical characteristics of these infections.Material and methodsA retrospective review of hospital admitted patients with a diagnosis of folliculitis, cellulitis, erysipelas, abscesses, hidradenitis, furuncle, impetigo, fasciitis and Fournier's gangrene. Cases were extracted from the data base of diagnostic codes of the Archive and Clinical Documentation Department of Son Llàtzer Hospital from January 2002 to November 2011.ResultsWe studied 996 episodes in 841 hospitalized patients with any diagnosis of SSTIs. Cellulitis/erysipelas (66.7%) was the most frequently diagnosed condition, with 77% of all SSTIs being community acquired, and the majority of patients had comorbidities, mainly diabetes (33%) and heart failure (17.7%). The most frequent isolated microorganism was S. aureus (35.1%), in 19 (12.9%) cases with methicillin-resistance (MRSA), 84.2% of them were nosocomial or health care acquired. Monotherapy with aminopenicillin with clavulanic acid was the empiric treatment most frequently used (35.5%). New antibiotics for Gram-positive cocci (linezolid, daptomycin, and tigecycline) were used in patients with comorbidities that presented more complications (P < .001) and more risk of mortality (P = .001). During admission 10.9% of patients died, but only in 2.7% of them mortality was related to the SSTIs.ConclusionsSSTIs attended most frequently in hospitalized patients are mainly cellulitis/erysipela, the majority community acquired. MRSA infections are mainly health care related. Use of new antibiotic for Gram-positive cocci was limited. |
| |
Keywords: | Infecciones de piel y partes blandas Pacientes hospitalizados Prevalencia Staphylococcus aureus resistente a la meticilina Tratamiento Pronó stico |
本文献已被 ScienceDirect 等数据库收录! |
|