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Increased plasma IL-6, IL-8, TNF-alpha,and G-CSF in Japanese narcolepsy
Authors:Susumu Tanaka  Makoto HondaHiromi Toyoda  Tohru Kodama
Affiliation:Sleep Disorders Project, Department of Psychiatry and Behavioral Science, Tokyo Metropolitan Institute of Medical Science, Kamikitazawa 2-1-6, Setagaya-ku, Tokyo 156-8506, Japan
Abstract:Narcolepsy is a chronic hypersomnia involving excessive daytime sleepiness and cataplexy. Some susceptibility genes and environmental factors suggest that post-infectious immunological alterations underlie its pathophysiology. To investigate the immunological alterations in narcolepsy patients, we examined cytokines.
Keywords:Narcolepsy   Cytokine   Sleep   IL-8   G-CSF
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