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Prevalence of Lynch syndrome in a Middle Eastern population with colorectal cancer |
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| Authors: | Abdul K. Siraj PhD Sarita Prabhakaran MD Prashant Bavi MD Rong Bu MDPhD Shaham Beg MD Mohsen Al Hazmi MBBS Maha Al‐Rasheed BSc Mohammed Al‐Assiri MD Rami Sairafi MD Fouad Al‐Dayel MD Nasser Al‐Sanea MD Shahab Uddin PhD Khawla S. Al‐Kuraya MD FCAP |
| Affiliation: | 1. Human Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia;2. Department of Surgery, Security Forces Hospital, Riyadh, Saudi Arabia;3. Department of Pathology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia;4. Colorectal Unit, Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia;5. College of Medicine, Alfaisal University, Riyadh, Saudi Arabia |
| Abstract: | |
| Keywords: | colorectal cancer (CRC) hereditary nonpolyposis colorectal cancer (HNPCC) Lynch syndrome (LS) microsatellite instability (MSI) mismatch repair (MMR) genes mutL homolog 1 (MLH1) mutS protein homolog 2 (MSH2) mutS protein homolog 6 (MSH6) postmeiotic segregation increased 2 (PMS2) |