白内障手术后后囊膜混浊的量化比较

目的 评估白内障术后疏水件丙烯酸人工晶状体SensarAR40e和硅胶人工晶状体的后囊膜混浊(PCO),并用能客观评估PCO的软件量化分析.方法 共选择98只眼行标准的超声乳化白内障吸除术,人工晶状体囊袋内固定.所有眼随机植入Sensar AR40e或硅胶人工晶状体,但同一患者植入的人工晶状体必须不同.在第1年和第2年时后照法拍摄后囊膜图像,通过去除浦肯野反光、增强对比度、过滤后增强低密度的PCO等方法处理后用POCO软件分析对比.结果 术后1年疏水性丙烯酸人工晶状体PCO为(0.32±0.13)%硅胶人工晶状体为(0.39±0.17)%(P=0.37).2年时疏水性丙烯酸人工晶状体PCO为(0.42±0.20)%,硅胶品状体为(0.34±0.18)%(P=0.50).患者术后1年,2年时疏水性丙烯酸人工品状体PCO的严重级别分别是(0.50±0.30)和(0.82±0.58),‘亏硅胶人工晶状体的(0.63±0.35)和(0.55±0.35)相比,无统计学意义(P＜0.05).结论 PCO后囊膜混浊量化分析系统提供了客观而且可重复性强的量化PCO的方法,也是研究预防PCO技术的有力工具.

Quantification of posterior capsular opacification after cataract surgery

Objective To evaluate posterior capsular opacification(PCO)with hydrophnbie and use a software program developed to provide an objective assessment of the amount of PCO in digital images of the posterior capsule to quantify PCO.Methods Ninety-eight eyes underwent standardized phacoemulasification and "in the bag" IOL placement.They were randomized to receive a three piece lens of hydrophobic or silicone,but lens materials is different in one case.On years 1 and 2 digitized retroillumination images were taken of the posterior capsule.Images were analyzed by POCO software program,removing the Purkinje light reflexes,contrast enhancement,filtering to enhance low-density PCO.Results Percentage PCO were in 0.32±0.13 ofhydrophobic acrylic IOLs at year 1,compared with 0.39±0.17 of silicone(P=0.37).At year 2,percentage PCO were in 0.42+0.20 with hydrophobic acrylic IOLs,0.344±0.18 with silicone IOLs(P=0.50).Of those patients with PCO at year 1 and year 2,the severity grades were 0.50±0.30 and 0.82±0.58 of hydrophobic acrylic cases,compared with 0.63±0.35 and 0.55±0.35 of patients with silicone IOLs(P=0.52,P=0.69).Conclusions The POCO system is capable of producing an objective and repeatable measurement of PCO that is relevant to assessing techniques of PCO prevention.