Platelet 5-HT uptake in post-stroke depression |
| |
| Authors: | S Barry O M Phillips D C Williams T G Dinan |
| |
| Affiliation: | Department of Psychiatry, Trinity College Medical School, St. James's Hospital, Dublin, Ireland. |
| |
| Abstract: | Serotonin (5-HT) uptake into platelets is reduced in functionally depressed patients. Depression following stroke (cerebrovascular accident; CVA) is common and severe. Sixteen patients who had suffered a CVA within 6 to 12 months and who were medication-free had blood taken for measurement of platelet 5-HT uptake. Seven of these patients were depressed. These were compared with age- and sex-matched hospital controls. No difference in platelet 5-HT uptake was found across these groups. |
| |
| Keywords: | platelet serotonin depression stroke |
|
