应用MSCT预测肝癌TACE术前碘化油沉积率研究

目的探讨MSCT在肝癌TACE术前预测碘化油沉积率的线性关系。方法回顾性分析2010年1月至2017年10月我院诊治的79例肝癌经TACE介入治疗病例,根据术前MSCT病灶强化面积是否超过50%划分为研究组(强化面积均≥50%,n=55)及对照组(强化面积均<50%,n=24),探讨两组的肿瘤碘油沉积率和近期疗效之间的差异。结果研究组肿瘤碘油沉积率和近期疗效均显著高于对照组。两组的TACE介入术后碘油沉积率Z与术前最大截面长径X均呈显著性负相关,与强化面积比Y呈显著性正相关,研究组回归线性方程式为:碘油沉积率Z=0.555-0.041X+0.458Y。结论 MSCT增强扫描动脉期的肿瘤强化面积与TACE术后碘油沉积率呈正相关,MSCT动脉期表现为富血供的原发性肝癌在TACE术后有较高的碘油沉积率和较好的近期疗效。

Prediction of Lipiodol Deposition Rate before TACE with MSCT

Objective To discuss the prediction value of lipiodol deposition rate before transcatheter arterial chemoembolization(TACE) with MSCT. Methods A retrospective analysis was made of 79 cases of liver cancer treated by TACE from January 2010 to October 2017 in our hospital. According to whether the enhanced area of MSCT before operation was more than 50%, they were divided into study group(enhanced area≥50%, n=55) and control group(enhanced area<50%, n=24). The difference between the two groups in tumor lipiodol deposition rate and short-term efficacy was discussed. Results The lipiodol deposition rate and short-term efficacy in the study group were significantly higher than those in the control group. There was a significant negative correlation between the lipiodol deposition rate Z after TACE intervention and the maximum cross-sectional length x before TACE intervention, and a significant positive correlation between lipiodol deposition rate Z and the enhanced area ratio y. The regression linear equation of the study group was: lipiodol deposition rate Z=0.555-0.041 X+0.458 Y. Conclusion The enhanced area of MSCT in arterial phase is positively correlated with the lipiodol deposition rate after TACE. The primary liver cancer with abundant blood supply in arterial phase of MSCT has a higher lipiodol deposition rate and a better short-term effect after TACE.