儿童可逆性胼胝体压部病变综合征的MRI诊断价值

目的探讨可逆性胼胝体压部病变综合征(RESLES)的MRI特点,提高对其诊断的准确性。方法回顾性分析5例RESLES患儿的临床及MRI资料。全部病例均行MRI平扫。结果 5例患儿首次MRI均表现为胼胝体压部的类圆形或椭圆形孤立性异常信号,T1WI呈等信号2例,稍低信号3例;5例T2WI及FLIAR均呈稍高信号;5例DWI均呈高信号;5例ADC图均呈低信号,ADC值范围0.352~0.526×10-3mm2/s,平均ADC值(mADC)为(0.429±0.072)×10-3mm2/s。所有病灶均无水肿及占位效应。所有患儿经治疗后5-13天复查颅脑MRI,显示病灶均消失。结论 RESLES是一种少见的临床与影像学综合征,临床症状轻微,预后良好,颅脑MRI具有特异性,能为该病的正确诊断提供帮助。

MRI Diagnostic Value of Reversible Splenial Lesion Syndrome in Children

Objective To investigate the MRI characteristics of reversible splenial lesion syndrome(RESLES), and to improve the diagnostic accuracy. Methods The clinical and MRI data of 5 cases of RESLES were analyzed retrospectively. All cases underwent conventional MRI imaging. Results All cases showed solitary circular or oval abnormal signal in the splenial of corpus callosum on the initial MRI. Lesions in 2 of 5 cases appeared as iso-intensity on T1 WI, and the other 3 cases demonstrated hypo-intensity. Lesions in 5 cases appeared as slightly hyper-intensity on T2 WI and FLAIR. Lesions in 5 cases were hyper-intensity on DWI, while the they were hypo-intensity on ADC, the range of ADC value was 0.352~0.526×10-3 mm2/s, and the mean ADC value(mADC) was(0.429±0.072)×10-3 mm2/s. No edema and occupying effect were found in all lesions. After 5-13 days of treatment, the original lesions were completely disappeared on the follow-up cerebral MRI. Conclusion RESLES is a rare clinicoradiological syndrome with mild clinical symptoms and good prognosis, the cerebral MRI features are special and help to the diagnosis of the disease.