CT联合MRI检查在脑胶质瘤术前诊断中的应用研究

目的旨在探讨CT联合MRI检查在脑胶质瘤术前诊断中的应用价值。方法选取我院2016年6月~2018年4月收治的脑胶质瘤患者45例,45例患者均进行了MRI及CT检查,收集患者临床资料、影像学资料,由两名副主任级医师对CT、MRI检查中的脑胶质瘤影像学表现特征进行总结,分析MRI联合CT在脑胶质瘤术前诊断中临床价值。结果 CT平扫脑胶质瘤主要表现均匀或者不均匀的低密度病灶,少数为混杂病灶,11例患者可见钙化影。增强扫描中,6例星形细胞瘤患者未见明显强化,17例星形细胞瘤明显强化,同时伴有不同程度的囊变液化坏死低密度区,6例患者呈现花环状强化。MRI平扫中胶质瘤实质部分主要表现为长T1、长T2信号;3例患者累及2个脑叶,3例患者累及3个脑叶,45例患者中以颞叶、额叶受累多见;增强扫描中脑胶质瘤强化特征主要为边缘强化、结节强化。CT联合MRI检查诊断脑胶质瘤的灵敏度、特异度分别为97.77%、100%,单纯CT检查诊断脑胶质瘤灵敏度(80.00%)、单纯MRI检查诊断脑胶质瘤特异度(82.22%)明显低于CT联合MRI检查,差异具有统计学意义(P<0.05)。结论 CT联合MRI检查诊断脑胶质瘤灵敏度、特异度高,可有效显示病灶累计范围、图像表现特征,为临床手术提供可靠资料。

Application of CT Combined with MRI in Preoperative Diagnosis of Glioma

Objective To explore the application value of CT combined with MRI in preoperative diagnosis of glioma. Methods 45 patients with glioma admitted to our hospital from June, 2016 to April, 2018 were selected. All 45 patients received MRI and CT examinations, and clinical and imaging data were collected. The imaging features of glioma in CT and MRI examinations were summarized by two deputy chief physicians, and the clinical value of MRI combined with CT in the preoperative diagnosis of glioma was analyzed. Results CT non-enhanced scan of glioma showed homogeneous or inhomogeneous low-density lesions, few of which were mixed lesions, and calcification was observed in 11 patients. In the enhanced scan, there was no significant enhancement in 6 patients with astrocytoma, while there were significant enhancement in 17 patients with astrocytoma, accompanied by different degrees of cystic liquefaction necrosis in the low-density region, and 6 patients showed annular enhancement. In MRI non-enhanced scanning, the parenchyma of glioma presented long T1 and long T2 signals. Three patients were involved in two lobes, three were involved in three lobes, and most of the 45 patients were involved in the temporal and frontal lobes. In enhanced scan, the enhancement features of glioma were mainly marginal enhancement and nodule enhancement.The sensitivity and specificity of CT combined with MRI in the diagnosis of glioma were 97.77% and 100%, respectively. The sensitivity(80.00%) of glioma diagnosed by CT alone and the specificity(82.22%) of glioma diagnosed by MRI alone were significantly lower than that of CT combined with MRI(P<0.05). Conclusion The sensitivity and specificity of CT combined with MRI in the diagnosis of glioma can effectively display the accumulative range of lesions and the features of image expression, providing reliable data for clinical surgery.