| 增强型体外反搏改善经皮冠状动脉介入治疗术后心肌无再流现象 |
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| 引用本文： | 陈小林,刘婷婷,余泽洪,刘俭,刘伊丽,刘冬红,马虹.增强型体外反搏改善经皮冠状动脉介入治疗术后心肌无再流现象[J].高血压杂志,2008(8). |
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| 作者姓名： | 陈小林 刘婷婷 余泽洪 刘俭 刘伊丽 刘冬红 马虹 |
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| 作者单位： | 江门市人民医院/心血管病研究所心内科;南方医科大学附属南方医院心内科;中山大学心血管病研究所/附属第一医院心内科; |
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| 摘 要： | 目的探讨增强型体外反搏(EECP)能否改善急性心肌梗死(AMI)靶血管重建后心肌无再流现象。方法靶血管重建后心肌无再流的 AMI 病人162例随机分为常规药物治疗组(n=81)。体外反搏治疗36 h 后,心肌声学造影(MCE)评估危险区心肌灌注。同时测量两组病人治疗前后血浆内皮素(ET)、一氧化氮(NO)和丙二醛(MDA)水平。结果反搏治疗组病人危险区心肌灌注明显改善,标化 A×β值(毛细血管灌注=毛细血管容积×充盈速率)从0.11±0.07升高到0.92±0.08(P<0.05);药物治疗组病人危险区心肌灌注无显著变化,标化 A×β值为0.10±0.09 vs 0.12±0.05(P>0.05)。反搏治疗组病人血浆 ET 水平从(113.6±44.1)ng/L 下降到(79.3±31.7)ng/L(P<0.05),MDA 水平从(5.8±0.6)ng/L 下降到(3.9±0.7)ng/L(P<0.05),NO 水平从(38.7±6.0)μmol/L 上升到(99.5±15.7)μmol/L(P<0.05);药物治疗组病人血浆 ET 水平从(119.3±43.1)ng/L 上升到(146.0±38.6)ng/...
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| 关 键 词： | 增强型体外反搏 急性心肌梗死 心肌灌注 无再流 心肌声学造影 |
Enhanced External Counterpulsation Improved No-reflow Phenomena in Myocardium After Percutaneous Coronary Intervention |
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| CHEN Xiao-lin LIU Ting-ting YU Ze-hong LIU Jian LIU Yi-li LIU Dong-hong MA Hong..Enhanced External Counterpulsation Improved No-reflow Phenomena in Myocardium After Percutaneous Coronary Intervention[J].Chinese Journal of Hypertension,2008(8). |
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| Authors: | CHEN Xiao-lin LIU Ting-ting YU Ze-hong LIU Jian LIU Yi-li LIU Dong-hong MA Hong |
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| Institution: | CHEN Xiao-lin~1 LIU Ting-ting~1 YU Ze-hong~1 LIU Jian~2 LIU Yi-li~2 LIU Dong-hong~3 MA Hong~3. 1.Department of Cardiology,Jiangmen Cardiovascular Institute/People\'s Hospital,Jiangmen 529000,2.Department of Cardiology,the Affiliated Southern Hospital,Medical University,Guangzhou,510515,3.Department of Cardiology,the Sun Yat-sen University Institute of Cardiovascular Disease/First Affiliated Hospital,Sun Yat-sen University of Heart Medicine,Guangzhou 510080,China |
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| Abstract: | Objective To explore the potential possibility of enhanced external counterpulsation(EECP)to improve myocardial no-reflow phenomenon after target coronary angioplasty in patients with acute myocardial infarc- tion(AMI).Methods One hundred sixty-two AMI patients with myocardial no-reflow after coronary angioplasty were randomly to receive EECP(n=81)or routine medical treatment(n=81).After 36 hours EECP,myocardial perfusion was evaluated by myocardial contrast echocardiography(MCE).Plasma levels of endothelin... |
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| Keywords: | Enhanced external counterpulsation Acute myocardial infarction Myocardial perfusion No-reflow Myocardial contrast echocardiography |
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