First description of an Escherichia coli strain producing NDM-1 carbapenemase in Spain |
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| Authors: | Solé Mar Pitart Cristina Roca Ignasi Fàbrega Anna Salvador Pilar Muñoz Laura Oliveira Inés Gascón Joaquim Marco Francesc Vila Jordi |
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| Affiliation: | Department of Clinical Microbiology and Barcelona Centre for International Health Research (CRESIB), Hospital Clinic-IDIBAPS, University of Barcelona, Spain. |
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| Abstract: | A carbapenem-resistant Escherichia coli strain (DVR22) was recovered from a stool specimen from a patient with traveler's diarrhea who had traveled to India. Molecular screening led to the first identification of NDM-1 in Spain. The bla(NDM-1) gene was located in a conjugative plasmid of ca. 300 kb that also contained the bla(CTX-M-15), bla(TEM-1), Δbla(DHA-1), and armA genes. In addition, bla(NDM-1) was preceded by an ISAba125 insertion element only found in Acinetobacter spp. |
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