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尿激酶型纤溶酶原激活系统与肺癌侵袭转移的关系及靶点治疗的研究
引用本文:康志强,姜斌,王雅杰. 尿激酶型纤溶酶原激活系统与肺癌侵袭转移的关系及靶点治疗的研究[J]. 中华肿瘤防治杂志, 2004, 11(11): 1213-1216
作者姓名:康志强  姜斌  王雅杰
作者单位:1. 武警福建省总队医院肿瘤科,福建,福州,350001
2. 第二军医大学长海医院肿瘤科,上海,200433
摘    要:探索肺癌侵袭与转移的分子生物学机制 ,寻找抑制肺癌转移的靶点治疗 ,是当前人们研究的一个重点部分。就尿激酶型纤溶酶原激活系统各成分与肺癌侵袭、转移的关系以及近年来关于靶点治疗的探索作一综述。

关 键 词:肺肿瘤/病理学  尿激酶/分析  纤溶酶原灭活剂/分析  肿瘤浸润  肿瘤转移  综述文献
文章编号:1009-4571(2004)11-1213-04
修稿时间:2002-12-17

uPA system associated with lung cancer invasion and metastasis and its therapeutic assessment
KANG Zhi-qiang,JIANG Bin,WANG Ya-jie. uPA system associated with lung cancer invasion and metastasis and its therapeutic assessment[J]. Chinese Journal of Cancer Prevention and Treatment, 2004, 11(11): 1213-1216
Authors:KANG Zhi-qiang  JIANG Bin  WANG Ya-jie
Affiliation:KANG Zhi-qiang1,JIANG Bin2,WANG Ya-jie2 1.Department of Medical Oncology,Fujian Provincial Corps Hospital,Chinese People's Armed Police Forces,Fuzhou 350001,P.R.China 2.Department of Medical Oncology,Changhai Hospital,Second Military Medical University,Shanghai 200433,P.R.China
Abstract:Looking insight into the molecular mechanisms of lung cancer invasion is a critical approach to screen targets for treating the disease.This report focuses on the role of the members of uPA superfamily and their potential therapeutic strategy in metastasis of lung cancer.
Keywords:lung neoplasm/pathology  urokinase/analysis  plasminogen inactivator/analysis  neoplasm invasion  neoplasm metastasis  literature review
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