整体长轴收缩期峰值应变率指标评价心肌梗死患者左室收缩功能

目的 探讨整体长轴收缩期峰值应变率指标在评价心肌梗死患者左室整体收缩功能中的应用价值.方法 对14例心肌梗死患者与20例健康对照者,采集心尖两腔、四腔及左室长轴切面二维超声图像,应用VVI技术测量左室各节段收缩期长轴峰值应变率(SRs)并取平均值得出左室整体长轴收缩期峰值应变率(GSRs).以常规二维超声心动图评价左室壁节段运动,计算室壁运动积分指数(WMSI),并应用Simpson双平面法计算左室射血分数(LVEF).应用脉冲波组织多普勒显像(PDTI)技术测量并计算二尖瓣环平均收缩期峰值速度(Sm).比较两组间各指标,评价GSRs指标与WMSI指标、Sm指标及LVEF指标的关系.结果 心肌梗死患者组及正常对照组GSRs、WMSI、Sm及LVEF分别为(-0.57±0.21)%和(-1.02±0.09)%、(1.90±0.80)和(1.10±0.30)、(6.20±1.50)cm/s和(9.80±1.30)cm/s、(32.90±7.10)%和(65.50±5.70)%,差异均有统计学意义(P<0.05),且GSRs与WMSI、Sm及LVEF均呈高度相关(r=0.97,-0.98,-0.93, P<0.0001).结论 GSRs是客观评价左室整体收缩功能的新指标.

Global left ventricular function of patients with post myocardial infarctionassessed by global longitudinal peak systolic strain rate index

Objective To detect the value of the global longitudinal peak systolic strain rate (GSRs) index in assessing the global left ventricular (LV) systolic function of patients with post myocardial infarction (PMI). Methods Fourteen PMI patients and 20 normal controls were enrolled in the study. The apical 2-chamber, 4-chamber and long axis views were acoustically captured. The segmental peak longitudinal systolic strain rate (SRs) was measured using VVI technique. GSRs was obtained by averaging the segmental SRs values. The LV wall motion was evaluated and the wall motion score index (WMSI) was calculated with conventional echocardiography. Left ventricular ejection fraction (LVEF) was also calculated by two dimensional conventional echocardiography. The mean mitral annulus peak systolic velocity (Sm) was obtained using pulsed tissue Doppler (PDTI) imaging technique. Results The parameters of GSRs, WMSI, Sm and LVEF in PMI group were (-0.57±0.21)%, (1.90±0.80), (6.20±1.50)cm/s, (32.90±7.10)%, and those in normal control group were (-1.02±0.09)%, (1.10±0.30), (9.80±1.30)cm/s, (65.50±5.70)%, respectively. GSRs highly correlated with WMSI, Sm and LVEF (r=0.97, -0.98, -0.93, respectively, P<0.0001). Conclusion GSRs can be regarded as a new parameter to evaluate the global LV systolic function.