| 复方冰硼冲洗液体外抑菌效果的评价 |
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| 引用本文： | 史彦,杨健,陈浩.复方冰硼冲洗液体外抑菌效果的评价[J].华西口腔医学杂志,2013,31(4):353-355. |
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| 作者姓名： | 史彦 杨健 陈浩 |
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| 作者单位： | 1.南昌大学附属口腔医院牙体牙髓病科；2.江西中医学院附属医院药剂科， 南昌330006 |
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| 基金项目： | 江西省科技支撑计划基金资助项目(项目编号：2008ZD07800)南昌大学科技基金(医科类)资助项目(项目编号：2008)江西省卫生厅中医药科研基金资助项目(项目编号：2012A167) |
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| 摘 要： | 目的 评价纯中药制剂复方冰硼冲洗液和冰硼冲洗液对4种牙髓病原菌的体外抗菌活性。方法 采用琼脂稀释法，测定复方冰硼冲洗液和冰硼冲洗液对4种厌氧病原菌牙龈卟啉单胞菌、中间普氏菌、具核梭杆菌和粪肠球菌的最小抑菌浓度（MIC）和最小杀菌浓度（MBC）。结果 2种冲洗液对4种厌氧病原菌均有抗菌作用，复方冰硼冲洗液的抗菌性优于冰硼冲洗液。粪肠球菌的抗药能力明显强于其余3种菌株。结论 纯中药制剂复方冰硼冲洗液具有良好的抗菌性，作为根管冲洗液可能是有优势的。
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| 关 键 词： | 复方冰硼冲洗液 根管冲洗 抗菌性 |
Evaluation on antimicrobial efficacy of Fufang Bingpeng irrigant: An in vitro study |
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| Shi Yan,Yang Jian,Chen Hao..Evaluation on antimicrobial efficacy of Fufang Bingpeng irrigant: An in vitro study[J].West China Journal of Stomatology,2013,31(4):353-355. |
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| Authors: | Shi Yan Yang Jian Chen Hao |
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| Institution: | 1. Dept. of Conservative Dentistry and Endodontics, Stomatology Hospital of Nanchang University, Nanchang 330006, China; 2. Dept. of Pharmacy, The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China |
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| Abstract: | Objective To evaluate the antimicrobial efficacy of Fufang Bingpeng irrigant and Bingpeng irrigant on four endodontic pathogen bacteria. Methods The agar dilution method was used to observe the antimicrobial activity of Fufang Bingpeng irrigant, Bingpeng irrigant against four selected endodontic pathogen bacteria（Porphyromonas gingivalis, Prevotella intermedius, Fusobacterium nucleatum, Enterococcus faecalis）. Minimum inhibitory concentration and minimum bactericidal concentration was examined. Results Two irrigants had the antimicrobial activity against the anaerobic microorganisms. The antimicrobial efficacy of Fufang Bingpeng irrigant was better than that of Bingpeng irrigant. Compared with others, Enterococcus faecalis had the strongest resistance. Conclusion Fufang Bingpeng irrigant has good antibacterial activity. As a root canal irrigant, Chinese medicine alteratives might be advantageous. |
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| Keywords: | Fufang Bingpeng irrigant root canal irrigation antimicrobial efficacy |
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