| 高压氧对周围神经损伤再生作用的实验研究 |
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| 引用本文： | 王秋根 高建章. 高压氧对周围神经损伤再生作用的实验研究[J]. 解放军医学杂志, 1991, 16(5): 332-335 |
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| 作者姓名： | 王秋根 高建章 |
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| 作者单位： | 第二军医大学长海医院骨科(王秋根，高建章，刘植珊)，第二军医大学长海医院骨科(赵杰) |
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| 摘 要： |
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| 关 键 词： | 周围神经损伤 高压氧 神经再生 |
THE EFFECT OF HYPERBARIC OXYGEN ON THE REGENERATION OF INJURED PERIPHERAL NERVE |
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| Wang Qiugen,Gao Jianzhang,Liu Zhishan,Zhao Jie. THE EFFECT OF HYPERBARIC OXYGEN ON THE REGENERATION OF INJURED PERIPHERAL NERVE[J]. Medical Journal of Chinese People's Liberation Army, 1991, 16(5): 332-335 |
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| Authors: | Wang Qiugen Gao Jianzhang Liu Zhishan Zhao Jie |
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| Affiliation: | Wang Qiugen,Gao Jianzhang,Liu Zhishan,Zhao Jie. Department of Orthopaedic Surgery,Changhai Hospital,Second Military Medical University,Shanghai. |
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| Abstract: | The experimental group and control group consist of 20 adult rats each. They were anesthetized with intraabdominal pentobarbital (30 mg/kg). The right sciatic nerves were divided and then re-joined with end-to-end anastamosis with microsurgical technique. The experimental group received 10 times of hyperbaric oxygen treatment (2ATA) of 90 minutes each, while the control group did not. The restoration of the nerve functions, histological changes, and the quantity of intranerve scar were observed in 10 days and 12 weeks after operation. The results indicated that the hyperbaric oxygen could reduce interstitial swelling of the nerve, regeneration of the axons and restoration of the nerve functions. The mechanism of its actions are discussed in the paper. |
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| Keywords: | Peripheral nerve injury Hyperbaric oxygen Regeneration of nerve Mechanism |
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