关节腔冲洗并注射透明质酸钠治疗轻度膝关节炎70例

目的探讨关节腔冲洗并注射透明质酸钠治疗轻度膝关节炎（knee osteoarthritis,KOA）的临床疗效。方法 2007年7月至2009年3月共收治70例KOA患者。随机分为两组,治疗组35例,采用关节腔冲洗配合透明质酸纳关节腔注射的二联疗法;对照组35例,单用玻璃酸钠关节腔注射。将两组治疗3个月和2年的疗效随访进行对比观察。结果全部获得随访,随访时间为0.5～2年,平均14个月。治疗后3个月随访,治疗组治愈率为82.8%,对照组为60%（P〈0.01）;治疗后末次随访,治疗组复发率为22%,对照组为37%（P〈0.01）。结论二联疗法是治疗KOA的一种简便、安全可靠、无副作用、疗效确切的方法。

Joint cavity flushing combined with injection of sodium hyaluronate in treating mild knee osteoarthritis in 70 patients

Objective To investigate clinical effect of joint cavity flushing combined with injection of sodium hyaluronate （HA） on the knee osteoarthritis.Methods Totally 70 patients with knee osteoarthritis were randomly divided into 2 groups（n = 35 ）.In observation group,joint cavity flushing and intra - articular injection of HA were used.And in control group,only injection of HA was applied.The outcomes of the 2 groups were compared after 3 months and 2 years.Results All the patients were followed up and the average duration was 14 months（ranged 6-24 months）.The cure rates in observation group and control group were 82.8%and 60%（P0.01） 3 months after treatment,respectively.The recurrence rate of observation group was lower than that of control group（22%vs 37%,P0.01）.Conclusion Joint cavity flushing combined with injection of sodium hyaluronate is a simple and reliable therapy on the treatment of knee osteoarthritis.