| 氟代脱氧葡萄糖在PET／CT致痫灶定位显像中的应用 |
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| 引用本文： | 王永玲,张工化,王清理,王芬.氟代脱氧葡萄糖在PET／CT致痫灶定位显像中的应用[J].中国基层医药,2010,17(21):2919-2920,3026. |
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| 作者姓名： | 王永玲 张工化 王清理 王芬 |
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| 作者单位： | 漯河市中心医院PET/CT科,河南省漯河,462000 |
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| 摘 要： | 目的探讨正电子药物18F氟代脱氧葡萄糖（18F-FDG）在正电子发射计算机（断层PET／CT）脑显像致痫灶定位中的应用。方法对32例癫痫患者行18F-FDG脑三维PET／CT显像，将其定位结果与头皮脑电图（EEG）、颅脑CT或MRI结果进行比较。结果PET／CT阳性检出率为90．6％（29／32），其中低代谢灶27例，高代谢灶2例，正常3例；EEG阳性检出率为65．6％（21／32），常规脑部CT或MRI阳性检出率为31．0％（10／32）。结论18F-FDG在PETJCT脑显像中对癫痫的定位诊断有较高的灵敏性和准确性。
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| 关 键 词： | 氟脱氧葡萄糖F18 正电子发射断层显像技术 |
Application of 18F-FDG PET/CT in epileptogenic zone localization |
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| WANG Yong-ling,ZHANG Gong-hua,WANG Qing-li,WANG Fen.Application of 18F-FDG PET/CT in epileptogenic zone localization[J].Chinese Journal of Primary Medicine and Pharmacy,2010,17(21):2919-2920,3026. |
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| Authors: | WANG Yong-ling ZHANG Gong-hua WANG Qing-li WANG Fen |
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| Institution: | . Department of PET/ CT Division, The Central Hospital of Luohe, Luohe, Henan 462000, China |
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| Abstract: | Objective To discuss the application of 18F-FDG PET/CT in epileptogenic zone localization.Methods Tirty-two patients with epilepsies were studied with interictal 18F-FDG PET/CT cerebral imaging,and all of them had scalp EEG,CT or MRI results for comparision.Results The sensitivity of 18F-FDG PET/CT was 90.6%,27 patients(84.5%) showed focal hypometabolism,2 patients(6.3%) showed focal hypermetabolism and rest 3 patients(9.4%) had negative result.The sensitivity of EEG was 65.6%(21/32),the sensitivity of CT and MRI was 31.0%(10/32).Conclusion 18F-FDG PET/CT was a sensitive and accurate image modality in the localization of epileptic foci. |
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| Keywords: | Fluorodeoxyglucose F18 Positron-emission tomography |
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