利巴韦林凝胶剂的制备和质量标准的研究 |
| |
引用本文: | 胡祥珍,乔海艳.利巴韦林凝胶剂的制备和质量标准的研究[J].解放军药学学报,2004,20(4):312-314. |
| |
作者姓名: | 胡祥珍 乔海艳 |
| |
作者单位: | 仁爱医院;常州市第一人民医院药剂科,江苏,常州,213003 |
| |
摘 要: | 目的 探讨利巴韦林凝胶剂的处方、制备方法和质控标准。方法 以卡波姆-940作凝胶基质,制备利巴韦林凝胶剂;采用一阶导数光谱法测定凝胶剂中利巴韦林的含量。结果 平均回收率为100.21%,RSD为0.82%(n=8)。结论 方法稳定、简便易行、快速、准确,可作为该制剂的质量控制方法。
|
关 键 词: | 利巴韦林 凝胶 一阶导数光谱法 质量控制 |
文章编号: | 1008-9926(2004)04-0312-03 |
修稿时间: | 2002年5月15日 |
Preparation and Study on the Quality Standard of Ribavirin Gel |
| |
Abstract: | Aim The formula,preparation method and quality standard of ribavirin gel were studied.Methods The ribavirin gel was prepared with Carbomer-940 which served as gel stroma.The first order derivative spectrophotometry was used for the determination of ribavirin in the gel.Results The average recovery was 100.21%and RSD was 0.82%(n=8).Conclusion This method was found to be stable,simple,accurate,and can be used for quality control. |
| |
Keywords: | Ribavirin Gel First order derivative spectrophotometry Quality control |
本文献已被 CNKI 维普 万方数据 等数据库收录! |