安徽省医院感染监控网医院感染病原菌分布及耐药性分析

目的了解医院感染病原菌的分布及细菌的耐药情况. 方法对全省医院感染监控网40所医院感染病原菌来源及细菌耐药进行统计分析. 结果在8 490例医院感染病例中分离出病原菌3 808株(45.30%);病原菌以革兰阴性菌为主,占42.33%,主要来源于下呼吸道,占38.81%;大肠埃希菌对庆大霉素耐药率67.93%,与阿米卡星相比,对两者耐药性差异有显著性(P<0.01),耐甲氧西林葡萄球菌为66.89%,分离出的病原菌对氨苄西林的耐药率均>60%,大多数病原菌对常用抗菌药物均有较高的耐药率. 结论医院感染细菌的耐药性日趋严重,应引起高度重视.

Distribution and Antibacterial Resistance of Nosocomial Infection Pathogens from Provincial Nosocomial Infection Surveillance System(PNISS)

OBJECTIVE To investigate the distribution and drug resistance of nosocomial infection pathogens. METHODS Statistical methods were used to analyse the data of pathogen's origin and drug resistance from 40 hospitals of PNISS. RESULTS A total of 3 808 strains were isolated from 8 490 nosocomial infection cases (45.30%), from which the Gram-negative bacilli were predominate(42.33%). The pathogens were principally isolated from under respiratory tract (38.81%). The rate of gentamicin-resistant Escherichia coli was 67.93%, as compared with amikacin, the difference between them were significant. The rate of meticillin-resistant staphylococcus was 66.89%. Isolated pathogens were all resistant to ampicillin, the rates of drug resistance were over 60%. Pathogens were showed high drug resistance to common antibiotics. CONCLUSIONS The emergence of drug-resistant pathogens will continue to be a serious problem, we must take it intimately.