| 曲美他嗪对陈旧性心肌梗死康复期运动耐量的影响 |
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| 引用本文： | 韩跃刚,田军,刘万秀,卢珊. 曲美他嗪对陈旧性心肌梗死康复期运动耐量的影响[J]. 中国组织工程研究与临床康复, 2002, 6(17): 2666 |
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| 作者姓名： | 韩跃刚 田军 刘万秀 卢珊 |
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| 作者单位： | 1.Henan Provincial Hospital，zhengzhou 450003，China;2.Baofeng Country Traditionac Chinese Medica l Hospital |
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| 摘 要： | Persistentinsufficientflowofcoronaryarterywillleadtohi－bernationofpartialmyocardiumfollowingmyocardialinfarctionduetocoronaryheartdisease，andthusdecreasingheartfunction，ex－ercisetolerance，andqualityoflifeduringrehabilitationphase．TMZ，theinhibitorof３－KAT，playsthecardinalroleinen－ergymetabolismofmyocardium．Inpresentstudy，weobservedim－pactofTMZonexercisetoleranceofpatientswitholdmyocardialinfarction．１Subjectsandmethod１．１Subjects５８patientssufferedfromcoronaryscopyorclini－…
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Effect of trimetazidine on exercise capacity of the patients with old myocardial infarction during recovery period |
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| HAN Yue-gang,TIAN Jun,LIU Wan-xiu,LU Shan. Effect of trimetazidine on exercise capacity of the patients with old myocardial infarction during recovery period[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(17): 2666 |
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| Authors: | HAN Yue-gang TIAN Jun LIU Wan-xiu LU Shan |
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| Abstract: | Objective To investigate the effect of trimeta zidine(TMZ )on ex ercise capacity of the patients with old myocardial infarction during recovery p eriod.Method28patients were administered hitra les,blockers and antipemic ag ents.30patients were administered TMZ 20mg tid.After 12weeks ,we compar ed ni trite expenditures,time to onset of angina after exercise,the time to 1 mm ST segment depression after exercise and rate pressure product.Result Nitrit e expenditures per week were s ignificantly reduced than before tr eatment and c omprehensive group(P <0.001).The rate pressure product of TMZ did n' t change significantly(P >0.05).Conclusion TMZ may increase exercise capac ity of patients with old myocardial infa rction. |
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| Keywords: | trimetazidine old m yocardial infa rction exercise capacity _ |
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