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Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer
Authors:Ken-ichi Fujita  Yuichi Ando  Fumio Nagashima  Wataru Yamamoto  Hisashi Eodo  Kazuhiro Araki  Keiji Kodama  Toshimichi Miya  Masaru Narabayashi  Yasutsuna Sasaki
Affiliation:(1) Department of Clinical Oncology, Saitama Medical University, 38 Morohongou, Moroyama-cho, Iruma-gun, Saitama 350-0495, Japan;(2) Project Research Laboratory, Research Center for Genomic Medicine, Saitama Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama 350-1241, Japan
Abstract:
Keywords:Irinotecan  SN-38  Polymorphism   UGT1A7    UGT1A9    UGT1A1*6
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