| 表皮生长因子对MDPC-23细胞增殖和ALP活性的影响 |
| |
| 引用本文： | 刘晗,何文喜.表皮生长因子对MDPC-23细胞增殖和ALP活性的影响[J].临床口腔医学杂志,2004,20(7):399-400. |
| |
| 作者姓名： | 刘晗 何文喜 |
| |
| 作者单位： | 第四军医大学口腔医学院牙体病科,陕西,西安,710032 |
| |
| 摘 要： | 目的 :观察表皮生长因子 (epidermalgrowthfactor ,EGF)对成牙本质细胞系MDPC -2 3细胞增殖和碱性磷酸酶 (alkalinephosphatase ,ALP)活性的影响。 方法 :细胞培养、MTT比色测定法和碱性磷酸酶活性测定法。结果 :在一定浓度范围内 ,EGF明显促进MDPC -2 3细胞增殖 ,抑制MDPC -2 3细胞内碱性磷酸酶活性 ,并呈一定的剂量依赖性。结论 :EGF能促进成牙本质细胞增殖 ,而抑制其分化
|
| 关 键 词： | 1 25-二羟维生素D3 增殖 碱性磷酸酶 分化 |
| 文章编号： | 1003-1634(2004)07-0399-02 |
The effect of 1,25-(OH)2D3 on the proliferation and ALP activity of MDPC-23 cells |
| |
| LIU Han,HE Wen-xi.College of Stomatology,The Fourth Military Medical University,Xi'an ,China.The effect of 1,25-(OH)2D3 on the proliferation and ALP activity of MDPC-23 cells[J].Journal of Clinical Stomatology,2004,20(7):399-400. |
| |
| Authors: | LIU Han HE Wen-xiCollege of Stomatology The Fourth Military Medical University Xi'an China |
| |
| Institution: | LIU Han,HE Wen-xi.College of Stomatology,The Fourth Military Medical University,Xi'an 710032,China |
| |
| Abstract: | Objective:To examine the effects of epidermal growth factor(EGF) on the proliferation and alkaline phosphatase (ALP)of odontoblast cell line MDPC-23. Method:Cell culture, MTT colorimetric assay and assay of ALP activity were used.Result:EGF significantly promoted the proliferation of MDPC-23 cells, while inhibited greatly ALP activity of cells in a dose-dependent manner. Conclusion: EGF could inhibit the proliferation, and promote the differentiation of odontoblast cells. |
| |
| Keywords: | epidermal growth factor proliferation alkaline phosphatease differentiation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
