脂调康胶囊对高脂血症患者血清胰岛素样生长因子-2的影响

目的 观察脂调康胶囊对高脂血症(hyperlipidemia，HLP)患者血清胰岛素样生长因子-2(insulin-like growth factor，IGF-2)的影响。方法 将186例HLP患者随机分为治疗组124例和对照组62例，治疗组服用脂调康胶囊，对照组服用脂必妥片，8周为1个疗程，治疗前后检测血脂及血清IGF-2的变化．结果 脂调康胶囊在降低HLP患者血脂的同时，可显著升高血清IGF-2的含量。结论 脂调康胶囊通过升高血清IGF-2的含量，抑制血管内皮细胞凋亡，改善HLP患者胰岛素抵抗状态，阻止HLP的发展．

Effect of Zhitiaokang Capsule on Serum Insulin like Growth Factor-2 in Patients with Hyperlipidemia

Objective To observe the effect of Zhitiaokang capsule (ZTK) on serum insulin like growth factor 2 (IGF 2) in patients with hyperlipidemia (HLP). Methods Patients with HLP were randomly divided into the treated group ( =124) and the control group ( =62), they were treated by ZTK and Zhibituo tablet respectively for 8 weeks as one therapeutic course. The changes of blood lipids and serum IGF 2 before and after treatment were observed. Results ZTK could significantly reduce blood lipids and increase serum content of IGF 2. Conclusion ZTK could improve the insulin resistant status and inhibit the development of hyperlipidemia in patients by means of raising serum content of IGF 2 and suppressing vascular endothelial cell apoptosis.