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化疗药物膀胱灌注预防浅表性膀胱癌术后复发
引用本文:虞宗学 刘建民. 化疗药物膀胱灌注预防浅表性膀胱癌术后复发[J]. 蚌埠医学院学报, 1998, 23(4): 223-224
作者姓名:虞宗学 刘建民
作者单位:蚌埠医学院附属医院泌尿外科
摘    要:目的:探讨用化疗药膀胱内灌注预防浅表性膀胱癌术后复发。方法:将患者随机分为噻替哌组(35例),丝裂霉素C组(32例),分别用化疗药物行膀胱内灌注,观察1 ̄3年复发率,并与对照组(未灌药22例)作比较。

关 键 词:膀胱肿瘤 复发 预防 药物疗法 灌注疗法

Bladder irrigation of chemotherapeutic drugs for preventing relapse of superficial bladder cancer
Yu Zongxue,Liu Jianmin,Zheng Zheming. Bladder irrigation of chemotherapeutic drugs for preventing relapse of superficial bladder cancer[J]. Journal of Bengbu Medical College, 1998, 23(4): 223-224
Authors:Yu Zongxue  Liu Jianmin  Zheng Zheming
Abstract:Objective:To prevent relapse of superficial bladder cancer by irrigating bladder post operatively with chemotherapeutic drugs.Methods:The patients were divided into three groups:(A)treated with thiotepa(35 cases),(B)treated with mitomycin C(32 cases) and (C)control group(22 cases),and followed up from 1 to 3 years.Results:3 year tumor relapse rates were 48.6%,40.6% and 77.3% respectively.The rate of relapse in therapeutic groups was significantly less than that in control group( P <0.05).Median times of relapse were 22.7 ,29.2 and 10.8 months respectively.The survival time in A and B groups was longer than that in control group( P <0.01).Conclusions:Bladder irrigation with thiotepa and mitomycin C is effective in preventing relapse of superficial bladder cancer.
Keywords:bladder neoplasms  combine therapy  recurrence
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