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百草降脂灵对鹌鹑高脂血症和动脉粥样硬化的作用
引用本文:潘建新,张克平,顾振纶.百草降脂灵对鹌鹑高脂血症和动脉粥样硬化的作用[J].苏州大学学报(自然科学版),2001,21(6):646-648.
作者姓名:潘建新  张克平  顾振纶
作者单位:潘建新(苏州大学药学系,药理学教研室,苏州,215007)       张克平(苏州大学药学系,药理学教研室,苏州,215007)       顾振纶(苏州大学药学系,药理学教研室,苏州,215007)
摘    要:目的观察百草降脂灵对鹌鹑高脂血症的降脂作用和动脉粥样硬化的影响.方法鹌鹑喂以高脂饲料同时灌服百草降脂灵60d后,测定血脂含量和观察动脉粥样硬化程度.结果百草降脂灵能明显降低血清中TC、TG 、LDL-C水平和TC/HDL-C比值,也可使主动脉斑块面积和泡沫细胞减少,肝重量系数降低, 肝脂肪变性程度减轻.结论百草降脂灵有明显的降血脂和预防动脉粥样硬化的作用.

关 键 词:百草降脂灵  高脂血症  动脉粥样硬化
文章编号:1000-5749(2001)06-0646-03
修稿时间:2001年8月24日

The Experimental Study on Hyperlipidemia and Atherosclerosis of Baicaojiangzhiling in Partridge
PAN Jian-xing,ZHANG Ke-ping,GU Zhen-lun.The Experimental Study on Hyperlipidemia and Atherosclerosis of Baicaojiangzhiling in Partridge[J].Suzhou University Journal of Medical Science,2001,21(6):646-648.
Authors:PAN Jian-xing  ZHANG Ke-ping  GU Zhen-lun
Abstract:Objective To investigate the effect on hyperlipidemia and atherosclerosis of Baicaojiangzhiling (BCJZL) in experimental hyperlipidemic partridges.Methods Partridges were fed high fat diet and administered with BCJZL for 60 days. The levels of serum lipid were measured and the course of injury restoration of aorta wall were observed.Results BCJZL obviously lowered serum TC, TG, LDL-C levels and TC/HDL-C ratio, decreased foam cells and the degree of atherosclerotic plagues in the aorta of partridges, with simultaneous reduction of hepatic fatty degeneration and coefficient of hepatic weight.Conclusion BCJZL significantly lowers serum lipid and is useful for the treatment of atherosclerosis.
Keywords:Baicaojiangzhiling  hyperlipidemia  atherosclerosis
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