内镜下酚红喷洒染色诊断胃内幽门螺杆菌感染

目的：通过内镜喷洒酚红溶液，直接观察胃内颜色改变诊断胃内幽门螺杆菌感染。方法：14例慢性胃炎，11例消化性溃疡患者，于检查前1天的睡前服兰索拉唑30mg，内镜检查时从活检孔道将0．1％的酚红溶液与5％的尿素溶液喷洒于胃粘膜上，观察胃粘膜的颜色变化，分别取染色和非染色胃粘膜组织4块，2块做病检查，2块做细菌检查。结果：7例慢性胃炎胃粘膜染色，其中5例全胃染色，2例胃窦染色，9例消化性溃疡胃粘膜染色，其中2例全胃染色，5例胃窦染色，1例胃体染色，1例胃底染色。染色部位的病理检查、细菌培养（除1例因消化道出血连续3d静脉注射洛赛克40mg为阴性外）均阳性，未染色部位病理检查、细菌培养均阴性。结论：内镜下酚红喷洒染色可诊断胃内幽门螺杆菌感染。

Diagnosis of Helicobacter Pylori Infection of Gastric Mucus by Endoscopic phenol red test

Objective:To evaluate the dignosis of Helicobacter pylori infection of human gastric mucosa in vivo by endoscopic phenol test.Methods:14 patients with chroinc gastritis and 11 patients with peptic ulcer.Each patient was gaven 30mg of lansoprazole orally at bedtime the day before the test. 0.1% phenol red with 5% urea was sprayed over the entire surface of th gastric mucosa through the biopsy forceps channel.Four biopsy specimens were taken from coloured and non-coloured areas in the stomachs.Results:Among 14 patients with chronic gastritis,5 patients were diffuse from the antrum to the cardia,2 patients localised in the autrum of the stomach,7 patients were non-coloured.Among 11 patients with peptic ulcer,2 patients were diffuse from the antrum to the cardia,5 patients localised in the antrum of the stomach,2 patients were non-coloured.Positive outcomes were gained by pathological examination and bacterial culture for the stained areas and negative outcomes for the non-stained areas.Conclusions:The endoscopic phenol red test is a workable method for diagnosis of Helicobatcter pylori infection of gastric mucus.