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| 脉冲电场生物学效应及医学应用 | |
| 引用本文： | 黄华,宋关斌,王贵学,孙才新. 脉冲电场生物学效应及医学应用[J]. 生物医学工程学杂志, 2007, 24(1): 230-234 |
| 作者姓名： | 黄华 宋关斌 王贵学 孙才新 |
| 作者单位： | 1. 重庆大学,生物工程学院,生物力学及组织工程教育部重点实验室,重庆,400044 2. 重庆大学,生物工程学院,生物力学及组织工程教育部重点实验室,重庆,400044;重庆大学,电气工程学院,高电压及电工新技术教育部重点实验室,重庆,400044 3. 重庆大学,电气工程学院,高电压及电工新技术教育部重点实验室,重庆,400044 |
| 摘 要： | 脉冲电场能够产生许多不同于一般电场的生物学效应,尤其是纳秒脉冲对细胞的作用更为特殊。本文主要就不同的脉冲电场对细胞膜,胞内基质,细胞增殖等产生的生物学效应作相应的介绍。并在此基础之上分析多种生物效应在肿瘤治疗、基因治疗、以及药物输送等方面的研究现状。 |
| 关 键 词： | 脉冲电场 生物效应 肿瘤治疗 基因治疗 药物输送 |
| 修稿时间： | 2004-07-282004-12-13 |
Biological Effects and Their Applications in Medicine of Pulsed Electric Fields |
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| Huang Hua,Song Guanbin,Wang Guixue,Sun Caixin. Biological Effects and Their Applications in Medicine of Pulsed Electric Fields[J]. Journal of biomedical engineering, 2007, 24(1): 230-234 | |
| Authors: | Huang Hua Song Guanbin Wang Guixue Sun Caixin |
| Affiliation: | Key Laboratory for Biomnechanics & Tissue Engineering of the State Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China. |
| Abstract: | Pulsed electric fields can induce various kinds of biological effects that are essentially different from the normal electric fields,especially the interactions of Nanosecond Pulsed electric field(nsPEF) with cells.The biological effects of different pulsed electric fields on cell membranes,cytoplasmic matrixes,cell growth are introduced in this paper.Based on these effects,some applications of pulsed electric fields in cancer therapy,gene therapy,and delivery of drugs are reviewed in details. |
| Keywords: | Pulsed electric field Biological effects Cancer therapy Gene therapy Delivery of drugs |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |