冰冻切片诊断在甲状腺手术中的临床应用

目的 探讨冰冻切片在甲状腺手术中的临床应用，提高甲状腺冰冻切片诊断的准确率，减少甲状臃恶性肿瘤的漏诊。方法 回顾性对比观察248例甲状腺冰冻切片和石蜡切片。结果 冰冻切片诊断良性病变217例。恶性肿瘤22例，延迟9例；石蜡切片对照良性病变220例，恶性肿瘤28例，其中冰冻切片假阴性诊断3例（1．21％），冰冻切片确诊率为95．16％。结论 提高切片质量，掌握正确的取材方法，提高对甲状腺良恶性肿瘤的识别和鉴别能力，可提高甲状腺手术中冰冻切片诊断的准确率。

Clinical Application of Frozen Section in Thyroid Operation

Objective To discuss the clinical application of frozen section in thyroid operation so as to raise the rate of correct diagnosis.Methods A retrospective review was made to 248 frozen sections and paraffin sections.Results The frozen section diagnosis showed out 217 cases with benign lesion,22 cases with malignant tumor and there were 9 delayed diagnosis;in the control,the paraffin section showed 220 cases with benign lesion and 28 cases with malignant tumor;There were 3 false-negative diagnosis by frozen section (1.21%) and conformed diagnosis rate of frozen section reached 95.1%.Conclusions The correct diagnosing rate of frozen section in thyroid operation may be raised by increasing the section quality and improving the method.