| Ricin引起外周神经跨越神经节溃变的超微结构研究 |
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| 引用本文： | 杜彦军 秦秉志. Ricin引起外周神经跨越神经节溃变的超微结构研究[J]. 神经解剖学杂志, 1992, 8(1): 129-133 |
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| 作者姓名： | 杜彦军 秦秉志 |
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| 作者单位： | 第四军医大学解剖学教研室，第四军医大学解剖学教研室，第四军医大学解剖学教研室 西安 710032，西安 710032，西安 710032 |
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| 摘 要： | 为了探索神经毒剂Ricin对神经元溃变过程中的效用及最佳用量的效果,将10%Ricin注射于坐骨神经分支中,按梯次剂量将实验动物分组,分别于术后不同存活时间观察后根节神经元的溃变状态及过程,并在电镜下观察骶髓后连合核内的溃变终末像。结果表明注射6μl的10%Ricin、存活5-7天的材料,初级传入终末溃变的超微结构像最佳。Ricin所致的跨节溃变终末呈现多型性变化。
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| 关 键 词： | Ricin 跨越神经节溃变 超微结构 骶髓 猫 |
THE ULTRASTRUCTURE OF TRANSGANGLIONIC DEGENERATIVE TERMINALS IN THE SPINAL CORD BY APPLYING RICIN IN THE PERIPHERAL NERVES |
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| Du Yanjun,Qin Bingzhi,Li Jishuo. THE ULTRASTRUCTURE OF TRANSGANGLIONIC DEGENERATIVE TERMINALS IN THE SPINAL CORD BY APPLYING RICIN IN THE PERIPHERAL NERVES[J]. Chinese Journal of Neuroanatomy, 1992, 8(1): 129-133 |
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| Authors: | Du Yanjun Qin Bingzhi Li Jishuo |
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| Abstract: | Different dosages of 10% Ricin were injected respectively into the sciatic nerve of cats which were classified into different groups. At different survival times the degenerative changes of neurons in dorsal root ganglia (L7-S1) were observed with light microscope and the degenerated terminals were observed with electron microscope respectively. It was determined that injection of 10% Ricin 6μ1 and 6-8 days' survival was optimal for the observation of degenerated primary afferent terminals of sciatic nerve in the dorsal commissure nucleus (DCN).The transganglionic degeneration induced by Ricin was morphologically diversing. |
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| Keywords: | Ricin transganglionic degeneration sacral spinal cord ultrastructure cat |
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