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支气管肺泡灌洗对豚鼠支气管粘膜上皮损伤的研究
引用本文:王建平,窦建明,迟翔宇,穆冠玉. 支气管肺泡灌洗对豚鼠支气管粘膜上皮损伤的研究[J]. 山东大学学报(医学版), 1999, 0(1)
作者姓名:王建平  窦建明  迟翔宇  穆冠玉
作者单位:山东省立医院内科,山东省桓台县人民医院
摘    要:为观察支气管肺泡灌洗对豚鼠支气管粘膜上皮的影响,以临床所用方法对12只豚鼠行支气管肺泡灌注,灌毕切下右下肺叶,扫描电镜下对照观察灌洗与未灌洗豚鼠支气管粘膜上皮的变化。结果显示,灌洗后的豚鼠支气管粘膜上皮纤毛完全脱落,上皮细胞肿胀破裂。提示支气管肺泡灌洗可导致支气管粘膜上皮损伤,临床应用时要考虑其危害

关 键 词:支气管肺泡灌洗;病理学,临床;豚鼠

STUDY ON LESIONS OF BRONCHIAL MUCOSAL EPITHELIUM IN GUINEA PIGS BY BRONCHOALVEOLAR LAVAGE
Wang Jianping,Dou Jianming,Chi Xiangyu,et al. STUDY ON LESIONS OF BRONCHIAL MUCOSAL EPITHELIUM IN GUINEA PIGS BY BRONCHOALVEOLAR LAVAGE[J]. Journal of Shandong University:Health Sciences, 1999, 0(1)
Authors:Wang Jianping  Dou Jianming  Chi Xiangyu  et al
Abstract:To observe the effect of bronchial smucosal epithelium in guinea pigs by bronchoalveolar lavage(BAL), 12 guinea pigs were selected for BAL in the conventional clinical way. The sections from the right lower lungs of both the BAL and control groups were observed and compared by electronic microscopy. The cilia of bronchial mucosal epitheliun exfoliated completely and the epithelial cells were turgescent or ruptured in the experimental group. The result suggested that BAL may cause lesions to bronchial mucosal epithelium and its hazard should be taken into consideration in clinical application.
Keywords:Bronchoalveolar lavage  Pathology  clinical  Guinea pigs
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