3D打印PEEK材料在儿童颅骨成形术中的应用

目的 探讨3D打印聚醚醚酮（PEEK）材料在儿童颅骨成形术中的应用效果。方法 回顾性分析2017年1月至2019年6月使用3D打印PEEK材料进行颅骨成形术治疗的31例儿童颅骨缺损的临床资料。结果 所有患儿切口愈合良好，术后7~9 d拆线，头型美观，双侧基本对称。术后无感染、死亡、二次手术病例，1例出现硬膜下积液、1例出现皮瓣压伤。术后随访3个月至2年，CT复查显示颅骨双侧均对称良好，无癫痫发作、迟发型排斥反应、迟发型皮下积液、植入物外露、变形、移位等情况。结论 3D打印PEEK材料，和颅骨吻合精度高，对称性好，有良好的生物相容性和生物力学特性，是一种良好的儿童颅骨成形术的材料。

Application of three-dimensional-printed polyethere-therketone (PEEK) in pediatric cranioplasty

Objective To explore the application value of three-dimensional-printed polyetheretherketone (PEEK) in pediatric cranioplasty. Methods The clinical data of 31 children underwent cranioplasty using three-dimensional-printed PEEK from January 2017 to June 2019 were retrospectively analyzed. Results Incision healing was good in all children, and stitches were removed 7~9 days after surgery. The head shape was good in all children. There were no postoperative infections, deaths or secondary operations. Subdural effusion and flap compression injury occurred in 1 patient, respectively. At the last follow-up (range, 3 months~2 years), CT showed good symmetry on both sides of the skull. There were no seizures, delayed rejection, delayed subcutaneous effusion, implant exposure, deformation, or displacement. Conclusions Three-dimensional-printed PEEK is a good material for cranioplasty in children, which has advantages such as high precision and good symmetry for cranioplasty, and good biocompatibility and biomechanical properties.