The effects of economic sanctions on disease specific clinical outcomes of patients with thalassemia and hemophilia in Iran |
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| Institution: | 1. Department of Clinical Oncology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran;2. Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran;3. Department of Radiation Oncology, Mashhad University of Medical Sciences, Mashhad, Iran;4. Department of Biostatistics, Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran;5. Department of Radiation Oncology, Valiasr Hospital, Birjand University of Medical Sciences, Birjand, Iran;7. Department of Radiation Oncology, Faculty of Medicine, Iran Unioversity of Medical sciences, Tehran, Iran;11. Department of Health Research Methods, Evidence, and Impact, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada;12. Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada;1. Department of Economics, University of Texas at San Antonio, United States;2. Department of Applied Economics, Utah State University, United States;1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran 14114-13137, Iran;1. Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran;2. School of Health Policy and Management, York University, Toronto, ON M3J 1P3, Canada |
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| Abstract: | BackgroundThe sanctions applied by both the USA and the EU against Iran do not formally ban the exports of medicines; in practice, however, patients are experiencing great difficulty in securing the treatment. This article documents the impact of international sanctions on patients with thalassemia and hemophilia in southern Iran.MethodsThis survey examined the specific effects of external sanctions on the access of patients to their treatment between 2009 and 2012 from the point of view of patients with thalassemia (n = 69) and congenital coagulation disorders (n = 40) as well as related physicians (n = 20). Also, clinical manifestation and laboratory data of patients were compared in the same period.ResultsAccess to deferoxamine and Exjade as iron chelators in patients with thalasseamia, respectively, declined by almost 70% and half over this period. In addition, access to lyophilized coagulation factor VIII concentrate in hemophilia A dramatically dropped from 96.7% in 2009 to 3.3% in 2012. The clinical results showed a significant deterioration of arthropathy (P < 0.001) in hemophiliac patients and a significant increase in serum ferritin levels in thalassemia patients (P = 0.036).ConclusionSanctions had significant effect on public health on patients with thalassemia and hemophilia. |
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| Keywords: | Sanctions Thalassemia Shortage of medicine |
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